Osteoarthritis increase by age

Curcuma Longa Extract (Tumeric)

The history
Tumeric has been used in Ayurvedic medicine, for many conditions, including breathing problems, rheumatism, serious pain, and fatigue. Today, turmeric is used as a dietary supplement for inflammation; arthritis; stomach, skin, liver, and gallbladder problems; cancer; and other conditions.

Curcumin has a long established safety record. For example, according to JECFA (The Joint United Nations and World Health Organization Expert Committee on Food Additives) and EFSA (European Food Safety Authority) reports, the Allowable Daily Intake (ADI) value of curcumin is 0–3 mg/kg body weight. Several trials on healthy subjects have supported the safety and efficacy of curcumin.

Anti-inflammatory and antioxidant
Curcumin is the main active ingredient in turmeric. This bioactive substance has powerful anti-inflammatory effects at molecular level, can suppress many molecules known to play major role in inflammation. Many studies show that curcumin matches and even more effective than some of anti-inflammatory drugs, without the side effects in treating arthritis related joint inflammation. Thus, curcumin is well known of control knee pain from osteoarthritis.

Curcumin also has powerful antioxidant effects. It neutralizes free radicals on its own but also stimulates your body’s own antioxidant enzymes.

Curcumin has received worldwide attention for its multiple health benefits. Research suggests that curcumin can help in the management of:

• oxidative and inflammatory conditions,
• metabolic syndrome,
• arthritis,
• anxiety,
• exercise-induced inflammation and muscle soreness,
• enhancing recovery and subsequent performance in active people.

 

Boswellia Serrata Gum extract
Boswellia, also known as Indian frankincense, comes from the Boswellia serrata tree, native to India. It’s been used for thousands of years in Ayurveda and other traditional healing systems to treat conditions like arthritis, pain, fever, and heart disease.

It’s similar to turmeric in mechanisms of action and conditions treated; used together, curcumin and boswellia may have synergistic effects that make them more powerful than using each alone. In one study, a combination of boswellia and turmeric was significantly more effective in reducing pain than the prescription NSAID celecoxib, commonly used for arthritis.

Studies show that boswellia may reduce inflammation and useful in treating the following conditions:

• osteoarthritis (OA)
• rheumatoid arthritis (RA)
• asthma
• inflammatory bowel disease (IBD)

Because boswellia is an effective anti-inflammatory, it can be an effective painkiller and may prevent the loss of cartilage. Some studies have found that it may even be useful in treating certain cancers, such as leukemia and breast cancer.

 

Rheumatoid arthritis and osteoarthritis
The anti-inflammatory actions of boswellia have been shown in several studies to ease pain, reduce swelling, and improve mobility in people with arthritis or osteoarthritis. Some research shows a profound effect, including a reduction in arthritis symptoms by 45 to 67 percent, which is comparable to prescription medications, and a 35 percent reduction in inflammation.

It appears to be especially helpful in osteoarthritis of the knee; several studies have found significant reductions in knee pain, knee jerking, swelling, and pain while walking, and improvements in flexion in test subjects who took boswellia.

Unlike some herbs, which may take weeks to be effective, boswellia works quickly: in one study, boswellia extract reduced pain and considerably improved knee-joint functions, in some cases providing relief even within seven days.

Some research suggests that boswellia may interfere with the autoimmune process, which would make it an effective therapy for RA. Further research supports the effective anti-inflammatory and immune-balancing properties.

Vitamin B12 (METHYLCOBALAMIN)
Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis.  Due to its role in energy metabolism, vitamin B12 is frequently promoted as an energy enhancer and an athletic performance and endurance booster. Vitamin B12 deficiency causes tiredness, weakness, nerve problems, such as numbness and tingling in the hands and feet, can also occur.

Methylcobalamin is the activated form of vitamin B12, was regarded as painkilling vitamin in some countries from 1950. Methylcobalamin or its combined use with other agents has the potential analgesic effect in specific patients, for example, nonspecific low back pain; neck pain; diabetic neuropathic pain.

Methylcobalamin also help in

• improved nerve conduction velocity;
• promoted injured nerve regeneration, recovering the neuromuscular functions in peripheral hyperalgesia and allodynia;
• inhibited the ectopic spontaneous discharges from peripheral primary sensory neurons in neuropathic pain states.

Collagen Peptide
As  the cartilage weakens and the amount of collagen in your body decreases as you get older, the risk of developing degenerative joint disorders such as osteoarthritis increases. you may start to feel stiff, achy joints. Collagen helps maintain the integrity of your cartilage, which is the rubber-like tissue that protects your joints .

Collagen intake help reduce joint pain and alleviate symptoms of arthritis.  Studies have shown that taking collagen supplements may help improve symptoms of osteoarthritis and reduce joint pain. Studies have suggested this may lead to lower inflammation, better support of your joints and reduced pain

• Helps support deteriorated joint matrixes.
• Helps improve long-term joint comfort and mobility.
• Type I collagen is the strongest of all known collagen types.

Calcium Carbonate
Calcium is needed by the body for healthy bones, muscles, nervous system, teeth and heart. A naturally occurring element, calcium carbonate exists in oyster shells, limestone and chalk, and become calcium supplements. Elemental calcium is the amount of calcium actually absorbed by the body, for example, there is more elemental calcium in calcium carbonate compared with other form of Calcium. Calcium carbonate contains 40% of elemental calcium making it the highest concentration of calcium in supplement form for maximum absorption.

Each softgel (845 mg) contains:

• Turmeric root extract
• Bosswellia serrata gum extract (250 mg)
• Elemental calcium (as calcium carbonate)
• Vitamin B12 (0.5 mg)
• Collagen peptide (from salmon skin) (100 mg)

Used as health supplement

Adults: Take 1 capsule orally after meal once daily or as directed by your pharmacist or doctor

Keep out of reach of children. This product contains ingredients derived from seafood. Please consult your doctor or pharmacist before using this product if you are on other medicines.

• Store below 30°C. Protect from sunlight and moisture
• Best to consume within 2 months from open cap